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Symbol
Name
ID
Nfasc
neurofascin
MGI:104753
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
nervous system phenotype
abnormal Purkinje cell axon morphology
abnormal axon morphology
abnormal axon initial segment morphology
abnormal paranode morphology
abnormal paranodal axoglial junction morphology
abnormal synapse morphology
abnormal sciatic nerve morphology
abnormal oligodendrocyte physiology
abnormal action potential
impaired ability to fire action potentials
decreased nerve conduction velocity
Availability Mouse Genotype
Nfasctm1.1Brp/Nfasctm1.1Brp
Nfasctm1.1Brp/Nfasctm1.1Brp
Tg(Plp1-Nfasc*)1Brp/0
*
Nfasctm1.1Brp/Nfasctm1.1Brp
Tg(Plp1-Nfasc)2Brp/0
*
Nfasctm1.1Brp/Nfasctm1.1Brp
Tg(Nefl-Nfasc)1Brp/0
*
Nfasctm1Bhat/Nfasctm1Bhat
Cnptm1(cre)Kan/?  (conditional)
Nfasctm1Bhat/Nfasctm1Bhat
Tg(Mpz-cre)26Mes/?  (conditional)
Nfasctm1Bhat/Nfasctm1Bhat
Tg(Plp1-cre/ERT)3Pop/?  (conditional)
Nfasctm2Bhat/Nfasctm2Bhat
Cnptm1(cre)Kan/Cnp+  (conditional)
Nfasctm2Bhat/Nfasctm2Bhat
Tmem163Tg(ACTB-cre)2Mrt/0  (conditional)
Nfasctm1.1Brp/Nfasctm1.2Brp
Tg(Thy1-cre/ERT2)#Brp/0  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory